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Förslaget inkom 2005-01-19

Design and Implementation of a Laboratory Information Management System (LIMS)

OBS! ANSÖKNINGSTIDEN FÖR DETTA EXJOBB HAR LÖPT UT.
Diploma work /Masters thesis project at the Dept of Pharmaceutical biosciences, Uppsala University, Genetta Soft AB, Uppsala

Background:
The dept of pharmaceutical biosciences, div of pharmacology, is developing tools for rational drug design using a novel method called Proteochemometrics. The aim is to predict interactions for drug candidates with known receptors using computer models. The process requires handling of large amounts of data, which today is done manually
using text-files.

The department wants to implement a high throughput information management system with databases, barcoded sample handling, automated information exchange from laboratory instruments, and user-friendly interfaces.

The project is a collaboration with Genetta Soft AB, a recently started company specializing in software solutions for biological and pharmacological research.

Design a general LIMS ¿ laboratory information management system to store, manage, and retrieve information regarding the resources, analyses, and results in a laboratory.
Configure and implement a LIMS for the dept of pharmaceutical pharmacology. Interface against existing lab instruments.
Acquire and set up hardware (barcode readers, label writers,
computers etc).
Test the implemented system.

2 positions are available
Due to the expected workload and crosscientific nature of the project we require two persons; one with more biological/laboratory knowledge, and one with a background in computer science. However, it is one project and extensive collaboration between the two students will be a
necessity. The two positions are described below.

1. Information management and database design
Prerequisites
Database knowledge
Some java knowledge
Experience of laboratory work

2.Interface design and implementation
Prerequisites
Experienced java skills
Database knowledge
Eclipse experience is an advantage

Operating system:
We prefer Linux but Windows is also acceptable.

Development tools:
Java
Eclipse IDE
Hibernate as OO-relational mapping
Junit for testing

Other:
Ability to work independently with deadlines.

References:
http://www.limsource.com/intro.html
http://www.eclipse.org/
http://dev.eclipse.org/viewcvs/index.cgi/~checkout~/platform-ui-home/rcp/index.html
http://www.farmbio.uu.se/upload/avd2/jarl/publ.html

Questions:
PhD student Ola Spjuth ([email protected]) tel: 018-471 4281
PhD student Martin Eklund ([email protected]) tel: 018-471 4281
Prof. Jarl S. Wikberg ([email protected]) tel: 018-471 4238

Send your application and CV to:
Martin Eklund ([email protected])
http://maradona.farmbio.uu.se/index.php?option=com_content&task=view&id=29&Itemid=2

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Ola Spjuth
PhD Student
Department of Pharmaceutical Biosciences
Linnaeus Centre for Bioinformatics
Uppsala University, Sweden
Ph: +46-18-4716685




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