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Master degree project - GE Healthcare Uppsala
We are a $17 billion unit of General Electric Company (NYSE: GE), employing more than 46,000 people worldwide and serving healthcare professionals in more than 100 countries. We believe in our strategy - and we'd like you to be a part of it. As a global leader, GE can bring together the best in science, technology, business and people to help solve one of the world's toughest challenges and shape a new age of healthcare.
Something remarkable happens when you bring together people who are committed to making a difference - they do!
The master degree project will be positioned in the vaccines and recombinant proteins applications section within the Bioprocess media department. There will be two supervisors for the project from GE, one with cell culture competence and one with downstream purification of virus.
Master degree project:
There is a large unmet need for better analytical tools in viral vaccine development. The challenge in developing and optimizing a vaccine purification process is to reliably measure the yield, recovery and purity of the virus over each step of the purification process. This put strains on the quality, timeline and simplicity of the methods as process development generates high numbers of samples. Currently used virus particle quantification methods are either labor and time consuming or require expensive equipment.
The main focus of the project is to evaluate the Virus Counter, a commercial bench top flow cytometer which enables detection and quantification of virus particles in solution. It includes investigation and identification of parameters influencing the robustness, accuracy, precision and quantitation limits of the assay. The project also includes evaluation and development of a new sample preparation method for virus samples in combination with the Virus Counter and to compare the results from the virus flow cytometer with currently used method.
The model system will be live influenza virus produced in mammalian cells and the work take place in a BSL-2 classified lab.
For further information, please contact:
Anita Solbrand, 018-6121447
Last Day of Application: 15th of February. Please submit your application as soon as possible.
To Apply, please follow this link: http://jobs.gecareers.com/job/Uppsala-Master-degree-project-GE-Healthcare-Uppsala-Job/1709698/
Education: Molecular Biotechnology/Technical Biology/Molecular Biology or likewise
The applicant should have basic knowledge in molecular biology and virology, be able to work independently and accurately with curiosity and an open mind, and preferably have experience in analytical method development. Education in BSL-2 work with influenza virus will be provided.
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Informationen om uppsatsförslag är hämtad från Nationella Exjobb-poolen.