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Förslaget inkom 2007-06-28

Theoretical study of the magnetic separation of bio-functionalized nanoparticles in microfluidics channels

OBS! ANSÖKNINGSTIDEN FÖR DETTA EXJOBB HAR LÖPT UT.
At Chalmers University of Technology together with Imego Institute, there is one open position for a diploma work in the field of Microsystems and Life science.

Background:
This interdisciplinary European project “Biological diagnostic tools using Microsystems and supersensitive magnetic detection” focuses on development of new instrumentation for immunoassays and high throughput screening aiming for unprecedented performance in terms of sensitivity, speed and sample handling, by combining:
(i) bio-functionalized magnetic nanoparticles (ca. 100 nm);
(ii) high sensitivity magnetic detection (SQUIDs);
(iii) microfabricated Lab-on-Chip.

In order to improve the output signal, it would be preferable to sort the bio-functionalized nanoparticles by size and separate them from other biological materials.

Goal of the project:
Investigate the feasibility to use a magnetic field (permanent magnet or integrated coils) to handle and separate nanoparticles in a microchannel.

Method / organization:
* Litterature study
* Magnetic and fluidic simulations

The results should be presented in a written report and in a seminar.

The Department:
The research at the Department of Microtechnology and Nanoscience, MC2, covers a wide range of disciplines in microtechnology and nanoscience. Large efforts, experimental as well as theoretical, are directed at materials, devices and subsystems for future micro/nanoelectronics in the fields of microwave electronics, quantum devices, photonics, micro- and nanosystems, superconducting devices and circuits and molecular electronics just to mention a few.

The research at Solid State Electronics Laboratory focuses on device structures and components based on silicon and III-V materials, circuits and microsystems and circuit design in superconducting electronics - http://www.chalmers.se/mc2




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